There has been a notable increase activity in Peru related to the Globally Harmonized System (GHS) and chemical management in recent years. In line with regional and national trends, Peru approved a decree, and in May 2024, the Regulation of Chemical Substances (DS) was passed, incorporating GHS guidelines. By 2025, the approval of risk assessment guidelines is expected, followed by the launch of the National Registry of Chemical Substances (RENASQ) in 2026. By 2027, risk reduction and management measures are anticipated to be implemented. In 2028, the registration of chemical mixtures in RENASQ will commence, with the application of risk assessments projected to begin in 2029.