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mal test methods, advancing animal-free toxicology approaches.  Global Warm

h toxicity, and mechanistic support for toxicology studies e.g. carcinogenicity).

In the context of the authorization process, Member States Competent Authorities and/or the European Chemicals Agency (ECHA), on request of the European Commission, could prepare Annex XV dossiers for the identification of Substances of Very High

ECHA has added two new substances to the Candidate List of substances of very high concern (SVHCs) for authorization on 19 January 2021. Now the list contains 211 substances in total. These two substances were added to the Candidate List as th

Final screening assessment and proposed risk management approach  The Government of Canada under the Act of Canadian Environmental Protection Act (CEPA), has added selenium and 28 of its compounds to Schedule 1 (list of toxic substances).�

Canada’s health and environment ministries have urged the conditions on the use of phosphonic acid, P,P′-(1-hydroxydodecylidene)bis-, allowing the limited amounts of the anti-adhesive to be used in certain cosmetic products. Since the

On the 5th of  August, the Government of Canada nominated long-chain PFCAs, their salts and related compounds (also known as precursors) for consideration under the Stockholm Convention on Persistent Organic Pollutants (POPs). The Stockholm Conventi

As per section 74 of the Canadian Environmental Protection Act, 1999 (CEPA), the Minister of the Environment and the Minister of Health have conducted a screening assessment of Lotus corniculatus extract. This substance was identified as a

On the 18th of January 2022, ECHA advises on how to determine and apply dose selection for dose and reproductive toxicity. This is in alignment with OECD guidelines. The director of ECHA for Hazard Assessment said the amended REACH annexes and the gu

Transport Canada (TC) recently opened a discussion to revise Part 6 of the Transportation of Dangerous Products (TDG) and set new training requirements.  Published in the Canada Gazette Part 1 on 11 December 2021, the recommendations aim at prov

According to ECHA, there is a new intention to identify a Substance of Very High Concern (SVHC) from Belgium together with France. The substance of interest is 4,4'-sulphonyldiphenol (i.e. Bisphenol S (BPS), EC 201-250-5, CAS 80-09-1), and the follow

d the Chemical Substances Computational Toxicology and Exposure Prediction Platform. It wi

write in the journal Particle and Fibre Toxicology that the study also “emphasises the i

nogenic classifications by the National Toxicology Program (NTP) or the International Agen

final product test, risk assessment and toxicology test requirements.  Currently, the

A recent study by Health Canada introduced a new metric called Cumulative Health Risk from Exposure Load (CHREL), which provides insight into the cumulative health risks posed by multiple chemical exposures. This metric is based on data from the Cana

The U.S. Environmental Protection Agency (EPA) has announced a proposal to revise the regulatory definition of volatile organic compounds (VOCs) under the Clean Air Act (CAA). The proposed change would add (Z)-1-chloro-2,3,3,3-tetrafluoropropene, com

On June 17, 2023, the Canadian government put forward proposals to amend the regulations governing formaldehyde emissions from composite wood products. The aim of these proposed amendments is to provide clarity on the requirements for quality control

The National Health Commission of China (NHC) published notifications for 2023 food safety related national standards legislation plan and 2024 food safety related national standards legislation suggestion.  The 2023 national standards legislatio

lism, analytical methodology, residues, toxicology, good agricultural practice, and dietar