On March 14, 2024, the South Korean National Institute of Food and Drug Safety Evaluation published a draft of the ‘Guidelines for Alternatives to Animal Testing Methods’ to help improve the international competitiveness of the domestic cosmetics industry and non-clinical testing institutions related to toxicity tests. The draft contains the guidelines for the two test methods as follows. 

• Guidelines for Test No. 498: In vitro Phototoxicity - Reconstructed Human Epidermis Phototoxicity test method Skin phototoxicity for Cosmetics, etc. 

• Guidelines for ARE-Nrf2 Luciferase Keratinocyte Activation Test Method (OECD 442D) KeretinoSens TM for skin sensitization for Cosmetics, etc. 

Companies that have an opinion on the draft guideline, please reply to our association (email: jenko@kcia.or.kr ) by March 18, 2024.